Regular Physical Activity May Decelerate the “Epigenetic Clock”
Physical activity acts as a potent geroprotector, influencing not only overall health but also biological age. This conclusion comes from a comprehensive review published in the journal *Aging*, where scientists analyzed findings from dozens of studies involving both humans and animals.
The review revealed that consistent exercise can effectively slow down the “epigenetic clock”—the molecular mechanisms used to determine an organism`s true biological age. Notably, significant changes were observed in the blood and skeletal muscles of active individuals, showing a “rejuvenation” of cellular structures.
However, the impact of exercise was not uniform; it varied based on the individual`s fitness level, specific characteristics, and the organs undergoing change. For instance, in mice with high endurance, the deceleration of biological aging was noted not only in muscles but also in the heart, liver, and adipose tissue.
Experts emphasize that while exercise is not a universal “cure for aging,” the accumulated evidence positions it as one of the most accessible and effective methods for extending active longevity. Scientists now aim to unravel the precise molecular mechanisms behind these effects and develop personalized exercise regimens.
Researchers previously reported a halt in the increase of life expectancy. While each new generation in the first half of the 20th century gained an average of five and a half months in lifespan, this figure has shrunk to just two and a half months for those born after 1939.
